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Published in final edited form as: Anal Chem. 2015 Dec 15;88(1):1022–1029. doi: 10.1021/acs.analchem.5b03978

Abstract

Xenografts are a popular model for the study of the action of new antitumor drugs. However, xenografts are highly heterogeneous structures, and therefore it is sometimes difficult to evaluate the effects of the compounds on tumor metabolism. In this context, imaging mass spectrometry (IMS) may yield the required information, due to its inherent characteristics of sensitivity and spatial resolution. To the best of our knowledge, there is still no clear analysis protocol to properly evaluate the changes between samples due to the treatment. Here we present a protocol for the evaluation of the effect of 2-hydroxyoleic acid (2-OHOA), an antitumor compound, on xenografts lipidome based on IMS. Direct treated/control comparison did not show conclusive results. As we will demonstrate, a more sophisticated protocol was

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Purposeful Work Infusion Project

AAGS 201: Race, Ethnicity, and Feminist Thought with Leslie Hill

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AAWS 201: Race, Ethnicity and Feminist Thought with Leslie Hill

AFAM 227: #BlackLivesMatter with Cassandra Shepard

AFSO 221: Sociology of Immigration with Marcelle Medford

ANLS 205: Citizenship, Borders, and Belonging with Jacqueline Lyon

ANTH 339: Production and Reproduction with Elizabeth Eames

ANTH s34: Place-Making, Community-Building and Transformation in Kingston, Jamaica with Charles Carnegie

ANTH s10: Encountering Community with Danny Danforth

ANTH S12 – Race, Gender, and the Practices and Politics That Move Videogames From Imagination to Reality with Joshua Rubin

ANTH s12: Imagining Videogames: An Introduction to the Practices and Politics that Make Videogames Happen with Josh Rubin

ANWS 275: Gender Relations in Comparative Perspective with Elizabeth Eames

ASEC 24

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Kitten Natividad

Mexican-American actress, exotic dancer and porn star (1948–2022)

Kitten Natividad
Natividad in 2014
Born	Francesca Isabel Natividad (1948-02-13)February 13, 1948 Ciudad Juárez, Chihuahua, Mexico
Died	September 24, 2022(2022-09-24) (aged 74) Los Angeles, California, U.S.
Other names	Francesca 'Kitten' Natividad, Francesca Natividad, Frances Natividad
Height	5 ft 4 in (1.63 m)

Francesca Isabel Natividad (February 13, 1948 – September 24, 2022), known professionally as Kitten Natividad, was a Mexican-American spelfilm actress and exotic dancer. She was noted for her 44-inch (112 cm) bust, and appearances in cult films made bygd her ex-partner, director Russ Meyer.

Early years

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Natividad was born on February 13, 1948, in Ciudad Juárez, Chihuahua State, Mexico. She was the eldest of nine children. Natividad did not speak English until she was 10 years old. At that time, her mother married a U.S. ci