Med abrous biography of george
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This means bringing in new—but not obviously so—details, like a cheetah print carpet, reupholstering the circular booths with Bordeaux-colored leather, painting the brick (inside and out) a muted lilac, adding emerald pony walls, and installing a burlwood bar and display shelves. Everything looks right at home in the space, and like it could be from the ’60s—in a good way.
The team is nothing if not obsessive: think vintage sconces, refurbished Italian chairs from the ’80s, handmade Tiffany-style table lamps, and custom-made replicas of the Charles Hollis Jones’ Frank Sinatra bar stool. They even created their own family crest-style stained glass cheetah emblem to adorn the kitchen windows and impart some pop to the clubhouse-style restaurant.
“We noticed many old-school Italian restaurants had animals often associated with luxury Italian car brands as their emblem,” says Rose. “We went with the cheetah, which can be seen throughout the restaurant on the carpet, stained glass,
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Abstract
Electroconvulsive therapy, a fast-acting option for treatment-resistant depression, is modeled at the preclinical level through the induction of electroconvulsive seizures (ECS) in rodents. Recent studies from our group proved sex- and age-differences in the antidepressant-like response elicited by ECS in rats; while an antidepressant-like response was observed in male adolescent and adult rats (although with greater efficacy in adulthood), the same parameters rendered inefficacious in females of any age. To better understand the potential sex differences taking place at the molecular level that might be mediating these behavioral disparities, we evaluated the impact of a repeated treatment with ECS (95 mA for 0.6 s, 100 Hz, 0.6 ms) in adolescent and adult rats of both sexes. Several hippocampal markers of neuroplasticity, commonly regulated by most antidepressants, such as those of neurogenesis (cell proliferation, neurogenic differentiation, long-term cell survival) or m